迎来化学制造业的革新

利用MiChs制造的微混和器的论文介绍

Journal of Synthetic Organic Chemistry, Japan

Role of Flow Microreactors for Pharmaceutical Production: Screening of Reaction Conditions and Sample Preparation



通过微空间流动型的自由基环化反应(Radical Cyclization),实现以克为单位规模的天然产物的键合成中间体的合成

Spurring Radical Reactions of Organic Halides with Tin Hydride and TTMSS Using Microreactors, Fukuyama, T.; Kobayashi, M.; Rahman, M. T.; Kamata, N.; Ryu, I. Org. Lett. 2008, 10, 533.

通过微空间流动型的Sonogashira coupling反应,实现以100克为单位规模的蛋白分解酶抑制剂的合成

An Automated-Flow Microreactor System for Quick Optimization and Production: Application to 10- and 100-gram Order Productions of a Matrix Metalloproteinase Inhibitor Using a Sonogashira Coupling Reaction, Sugimoto, A.; Fukuyama, T.; Rahman, M. T.; Ryu, I. Tetrahedron Lett. 2009, 50, 6364.